Product Name: Indomethacin
CAS: 53-86-1
Molecular Formula: C19H16ClNO4
Molecular Weight: 357.78
Synonyms: indomethacin methanol solution;indomethacin crystalline;indomethacin usp

Indomethacin is a white or slightly yellow crystalline powder. Melting point 158-162°C. It is soluble in acetone, slightly soluble in ethanol, chloroform, ether, and almost insoluble in water. Tasteless and almost odorless.

Specification

Melting point                                155-162°C

Storage conditions                      Store at RT

Solubility                                       ethanol:50mg/mL,clear,yellow-green

Related substances(TLC)           ≤0.5%

Loss on drying                              ≤0.5%

Sulphated ash                               ≤0.1%

Heavy metals                                ≤20ppm

Related solvent                             ≤0.5%

Content                                          98.5-100.5%

Application

Cyclooxygenase (COX) inhibitor, which selectively inhibits COX-1; blocks the biosynthesis of prostatic cord.

It has obvious anti-inflammatory and antipyretic effects in medicine. It is mainly used for rheumatic complication, ankylosing spondylitis, osteoarthritis, etc. that are not easily tolerated or not effective to salicylic acid drugs.

Packaging

25 kg/fiber drum

Products :

CAS 53-86-1, Indomethacin, C19H16ClNO4
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